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玻璃-PDMS 微流控芯片的电渗性能研究

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发表于 2018-5-25 11:18:08 | 显示全部楼层 |阅读模式
玻璃-PDMS 微流控芯片的电渗性能研究
崔丽佳,王升高,张维,皮晓强,刘星星,陈睿
武汉工程大学湖北省等离子体化学与新材料重点实验室
RESEARCH ON THE ELECTRO-OSMOSIS PERFORMANCE OF GLASS/PDMS MICROFLUIDIC CHIPS
CUI Li-jia,WANG Sheng-gao,ZHANGWei,PI Xiao-qiang,LIU Xing-xing,CHEN Rui
Provincial Key Laboratory of Plasma Chemistry and Advanced Materials of Hubei Province,Wuhan Institute of Technology

摘要 以玻璃为基片的微流控芯片在制造上存在工艺复杂、加工周期长、成本高等问题。实验以载玻片和PDMS为原材料,采用湿法刻蚀和浇筑的方法在玻璃和PDMS上制备出较佳结构的微沟道,并分别与PDMS和玻璃不可逆封接,获得了玻璃-PDMS(沟道在玻璃上,A.玻璃-PDMS)、玻璃-PDMS(沟道在PDMS上,B.玻璃-PDMS)两种芯片。对A.玻璃-PDMS、B.玻璃-PDMS两种芯片进行了伏安特性研究,得出芯片的线性伏安特性的最高电压分别为1 990 V、1 050 V,此时所对应的场强分别为499 V·cm-1、263 V·cm-1。利用电流监测对芯片的电渗性能进行分析,发现电渗流速度随缓冲溶液pH值的升高而增大,表面活性剂SDS的添加能显著提高电渗速度的大小和稳定性。

关键词 : 电渗,  微流控芯片,  PDMS   

Abstract:Manufacturing of microfluidic chip based on glass has many problems like complex craft,long-term processing cycle and high cost. This experiment improves these problems with glass and PDMS as raw materials,makes wellstructured micro-channels on the glass and PDMS in the way of wet corrosion,and obtains two chips by irreversible sealing. In the research,glass/PDMS chip(channel in the glass)and glass/PDMS chip(channel in PDMS)are made and studied their volt-ampere characteristics. It is concluded that the highest voltage of the chip linear volt-ampere characteristics are 1 990 V,1 050 V,respectively,in accordance with the field strength of 499 V·cm-1and 263 V·cm-1. The electro-osmosis properties of microfluidic chips are analyzed by the method of current monitoring,whereby it is found that the electric seepage velocity grows with the increase of buffer solution pH and adding surfactant SDS can dramatically raise the velocity and stability of the electro-osmotic.

Key words: electroosmosis           microfluidic chips           PDMS

基金资助:国家自然科学基金(No.51272187、No.51442003)、湖北省自然科学基金(No.2013CFA012、No.2015CFB229)和湖北省科技厅(No.2015BAA093)

作者简介: 崔丽佳(1992-),男,湖北荆州公安人,硕士,从事电化学研究。
引用本文: 崔丽佳,王升高,张维,皮晓强,刘星星,陈睿. 玻璃-PDMS 微流控芯片的电渗性能研究[J]. 真空与低温, 2016, 22(4): 201-.       
CUI Li-jia,WANG Sheng-gao,ZHANGWei,PI Xiao-qiang,LIU Xing-xing,CHEN Rui. RESEARCH ON THE ELECTRO-OSMOSIS PERFORMANCE OF GLASS/PDMS MICROFLUIDIC CHIPS. journal1, 2016, 22(4): 201-.

文章来源:《真空与低温》杂志2016年22卷4期

刊出日期:2016-08-30

链接地址:http://www.lipcast.cn:81/zkydw/CN/abstract/abstract100.shtml


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